×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 5frb

PDB Information

PDB5FRB
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceASPERGILLUS FUMIGATUS
Primary Citation
Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14 alpha-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity.
Hargrove, T.Y., Garvey, E.P., Hoekstra, W.J., Yates, C.M., Wawrzak, Z., Rachakonda, G., Villalta, F., Lepesheva, G.I.
Antimicrob. Agents Chemother.
HeaderOxidoreductase
Released2015-12-16
Resolution2.990
CATH Insert Date07 May, 2017

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
E9QY26 E9QY26_ASPFU Aspergillus fumigatus Af293 14-alpha sterol demethylase Cyp51B
CATH-Gene3D is a Global Biodata Core Resource Learn more...