PDB 5fdr

PDB Links
Overview

PDB Information

PDB	5FDR
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods. Pelz, N.F., Bian, Z., Zhao, B., Shaw, S., Tarr, J.C., Belmar, J., Gregg, C., Camper, D.V., Goodwin, C.M., Arnold, A.L., Sensintaffar, J.L., Friberg, A., Rossanese, O.W., Lee, T., Olejniczak, E.T., Fesik, S.W. J.Med.Chem.
Header	Apoptosis/Apoptosis Inhibitor
Released	2015-12-16
Resolution	2.600
CATH Insert Date	10 Apr, 2016

PDB Images (9)

Image of CATH 5fdr

5fdr

PDB 5fdr

Image of CATH 5fdrA

5fdrA

PDB Chain 5fdrA

Image of CATH 5fdrB

5fdrB

PDB Chain 5fdrB

Image of CATH 5fdrC

5fdrC

PDB Chain 5fdrC

Image of CATH 5fdrD

5fdrD

PDB Chain 5fdrD

Image of CATH 5fdrA01

5fdrA01

CATH Domain 5fdrA01

Image of CATH 5fdrB01

5fdrB01

CATH Domain 5fdrB01

Image of CATH 5fdrC01

5fdrC01

CATH Domain 5fdrC01

Image of CATH 5fdrD01

5fdrD01

CATH Domain 5fdrD01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped
C	11 Apr, 2016	Chopped
D	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5fdrA01	10 May, 2016	1.10.437.10	Assigned
5fdrB01	10 May, 2016	1.10.437.10	Assigned
5fdrC01	10 May, 2016	1.10.437.10	Assigned
5fdrD01	10 May, 2016	1.10.437.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1