PDB 5fcr

PDB Information

PDB5FCR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Small-molecule factor D inhibitors targeting the alternative complement pathway.
Maibaum, J., Liao, S.M., Vulpetti, A., Ostermann, N., Randl, S., Rudisser, S., Lorthiois, E., Erbel, P., Kinzel, B., Kolb, F.A., Barbieri, S., Wagner, J., Durand, C., Fettis, K., Dussauge, S., Hughes, N., Delgado, O., Hommel, U., Gould, T., Mac Sweeney, A., Gerhartz, B., Cumin, F., Flohr, S., Schubart, A., Jaffee, B., Harrison, R., Risitano, A.M., Eder, J., Anderson, K.
Nat.Chem.Biol.
HeaderHydrolase
Released2015-12-15
Resolution1.250
CATH Insert Date06 Nov, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped
B 07 Nov, 2016 Chopped
C 07 Nov, 2016 Chopped
D 07 Nov, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5fcrA01 10 Nov, 2016 2.40.10.10 Assigned
5fcrA02 10 Nov, 2016 2.40.10.10 Assigned
5fcrB01 11 Nov, 2016 2.40.10.10 Assigned
5fcrB02 11 Nov, 2016 2.40.10.10 Assigned
5fcrC01 10 Nov, 2016 2.40.10.10 Assigned
5fcrC02 10 Nov, 2016 2.40.10.10 Assigned
5fcrD01 10 Nov, 2016 2.40.10.10 Assigned
5fcrD02 10 Nov, 2016 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P03953 CFAD_MOUSE Mus musculus Complement factor D
P03953 CFAD_MOUSE Mus musculus Complement factor D
P03953 CFAD_MOUSE Mus musculus Complement factor D
P03953 CFAD_MOUSE Mus musculus Complement factor D