PDB Information

PDB5EYK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceXenopus laevis
Primary Citation
Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases.
Sini, P., Gurtler, U., Zahn, S.K., Baumann, C., Rudolph, D., Baumgartinger, R., Strauss, E., Haslinger, C., Tontsch-Grunt, U., Waizenegger, I.C., Solca, F., Bader, G., Zoephel, A., Treu, M., Reiser, U., Garin-Chesa, P., Boehmelt, G., Kraut, N., Quant, J., Adolf, G.R.
Mol.Cancer Ther.
HeaderTransferase
Released2015-11-25
Resolution1.930
CATH Insert Date04 Sep, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2016 Chopped
B 05 Sep, 2016 Chopped
C 05 Sep, 2016 Rejected
D 05 Sep, 2016 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5eykA01 09 Sep, 2016 3.30.200.20 Assigned
5eykA02 09 Sep, 2016 1.10.510.10 Assigned
5eykB01 08 Sep, 2016 3.30.200.20 Assigned
5eykB02 08 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q6DE08 AUKBA_XENLA Xenopus laevis Aurora kinase B-A
Q6DE08 AUKBA_XENLA Xenopus laevis Aurora kinase B-A
O13024 INCEA_XENLA Xenopus laevis Inner centromere protein A
O13024 INCEA_XENLA Xenopus laevis Inner centromere protein A