PDB 5eol

PDB Information

PDB5EOL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
Cee, V.J., Chavez, F., Herberich, B., Lanman, B.A., Pettus, L.H., Reed, A.B., Wu, B., Wurz, R.P., Andrews, K.L., Chen, J., Hickman, D., Laszlo, J., Lee, M.R., Guerrero, N., Mattson, B.K., Nguyen, Y., Mohr, C., Rex, K., Sastri, C.E., Wang, P., Wu, Q., Wu, T., Xu, Y., Zhou, Y., Winston, J.T., Lipford, J.R., Tasker, A.S., Wang, H.L.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-11-10
Resolution2.200
CATH Insert Date15 May, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5eolA01 15 Jul, 2016 3.30.200.20 Assigned
5eolA02 15 Jul, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1
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