PDB Information

PDB5ELO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceCryptosporidium parvum (strain Iowa II)
Primary Citation
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Baragana, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J.A., Pisco, J.P., Peet, C., Dranow, D.M., Robinson, D.A., Jansen, C., Norcross, N.R., Vinayak, S., Anderson, M., Brooks, C.F., Cooper, C.A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T.E., Hallyburton, I., Horst, B.G., Hulverson, M.A., Ferguson, L., Jimenez-Diaz, M.B., Jumani, R.S., Lorimer, D.D., Love, M.S., Maher, S., Matthews, H., McNamara, C.W., Miller, P., O'Neill, S., Ojo, K.K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L.M., Scullion, P., Sharma, A., Shepherd, S.M., Shishikura, Y., Simeons, F.R.C., Stebbins, E.E., Stojanovski, L., Straschil, U., Tamaki, F.K., Tamjar, J., Torrie, L.S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F.J., Maser, P., Kyle, D.E., Winzeler, E.A., Myler, P.J., Wyatt, P.G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C.D., Gray, D.W., Fairlamb, A.H., Pisliakov, A.V., Walpole, C., Read, K.D., Van Voorhis, W.C., Gilbert, I.H.
Proc. Natl. Acad. Sci. U.S.A.
HeaderLigase/Ligase Inhibitor
Released2015-11-04
Resolution1.900
CATH Insert Date27 Nov, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Nov, 2016 Chopped
B 28 Nov, 2016 Chopped
C 28 Nov, 2016 Chopped
D 28 Nov, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5eloA01 23 Jan, 2017 2.40.50.140 Assigned
5eloA02 23 Jan, 2017 3.30.930.10 Assigned
5eloB01 23 Jan, 2017 2.40.50.140 Assigned
5eloB02 23 Jan, 2017 3.30.930.10 Assigned
5eloC01 23 Jan, 2017 2.40.50.140 Assigned
5eloC02 23 Jan, 2017 3.30.930.10 Assigned
5eloD01 23 Jan, 2017 2.40.50.140 Assigned
5eloD02 23 Jan, 2017 3.30.930.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q5CR27 Q5CR27_CRYPI Cryptosporidium parvum Iowa II Lysine--tRNA ligase
Q5CR27 Q5CR27_CRYPI Cryptosporidium parvum Iowa II Lysine--tRNA ligase
Q5CR27 Q5CR27_CRYPI Cryptosporidium parvum Iowa II Lysine--tRNA ligase
Q5CR27 Q5CR27_CRYPI Cryptosporidium parvum Iowa II Lysine--tRNA ligase