PDB Information

PDB5EK0
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceArcobacter butzleri, Homo sapiens
Primary Citation
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist.
Ahuja, S., Mukund, S., Deng, L., Khakh, K., Chang, E., Ho, H., Shriver, S., Young, C., Lin, S., Johnson, J.P., Wu, P., Li, J., Coons, M., Tam, C., Brillantes, B., Sampang, H., Mortara, K., Bowman, K.K., Clark, K.R., Estevez, A., Xie, Z., Verschoof, H., Grimwood, M., Dehnhardt, C., Andrez, J.C., Focken, T., Sutherlin, D.P., Safina, B.S., Starovasnik, M.A., Ortwine, D.F., Franke, Y., Cohen, C.J., Hackos, D.H., Koth, C.M., Payandeh, J.
Science
HeaderMetal Transport
Released2015-11-03
Resolution3.530
CATH Insert Date10 Jan, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Jan, 2016 Chopped
B 11 Jan, 2016 Chopped
C 11 Jan, 2016 Chopped
D 11 Jan, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5ek0A01 23 Jan, 2017 1.20.120.350 Assigned
5ek0A02 23 Jan, 2017 1.10.287.70 Assigned
5ek0B01 23 Jan, 2017 1.20.120.350 Assigned
5ek0B02 23 Jan, 2017 1.10.287.70 Assigned
5ek0C01 23 Jan, 2017 1.20.120.350 Assigned
5ek0C02 23 Jan, 2017 1.10.287.70 Assigned
5ek0D01 23 Jan, 2017 1.20.120.350 Assigned
5ek0D02 23 Jan, 2017 1.10.287.70 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q15858 SCN9A_HUMAN Homo sapiens Sodium channel protein type 9 subunit alpha
A8EVM5 A8EVM5_ARCB4 Arcobacter butzleri RM4018 Ion transport protein
Q15858 SCN9A_HUMAN Homo sapiens Sodium channel protein type 9 subunit alpha
A8EVM5 A8EVM5_ARCB4 Arcobacter butzleri RM4018 Ion transport protein
Q15858 SCN9A_HUMAN Homo sapiens Sodium channel protein type 9 subunit alpha
Q15858 SCN9A_HUMAN Homo sapiens Sodium channel protein type 9 subunit alpha
A8EVM5 A8EVM5_ARCB4 Arcobacter butzleri RM4018 Ion transport protein
A8EVM5 A8EVM5_ARCB4 Arcobacter butzleri RM4018 Ion transport protein