Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.
Garcia Fortanet, J., Chen, C.H., Chen, Y.N., Chen, Z., Deng, Z., Firestone, B., Fekkes, P., Fodor, M., Fortin, P.D., Fridrich, C., Grunenfelder, D., Ho, S., Kang, Z.B., Karki, R., Kato, M., Keen, N., LaBonte, L.R., Larrow, J., Lenoir, F., Liu, G., Liu, S., Lombardo, F., Majumdar, D., Meyer, M.J., Palermo, M., Perez, L., Pu, M., Ramsey, T., Sellers, W.R., Shultz, M.D., Stams, T., Towler, C., Wang, P., Williams, S.L., Zhang, J.H., LaMarche, M.J.
J.Med.Chem.