PDB 5egm

PDB Information

PDB5EGM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Development of a novel tricyclic class of potent and selective FIXa inhibitors.
Meng, D., Andre, P., Bateman, T.J., Berger, R., Chen, Y.H., Desai, K., Dewnani, S., Ellsworth, K., Feng, D., Geissler, W.M., Guo, L., Hruza, A., Jian, T., Li, H., Metzger, J., Parker, D.L., Reichert, P., Sherer, E.C., Smith, C.J., Sonatore, L.M., Tschirret-Guth, R., Wu, J., Xu, J., Zhang, T., Campeau, L.C., Orr, R., Poirier, M., McCabe-Dunn, J., Araki, K., Nishimura, T., Sakurada, I., Hirabayashi, T., Wood, H.B.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-10-27
Resolution1.840
CATH Insert Date29 Nov, 2015

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped
B 30 Nov, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
5egmA01 03 Dec, 2015 2.40.10.10 Assigned
5egmA02 03 Dec, 2015 2.40.10.10 Assigned
5egmB00 03 Dec, 2015 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00740 FA9_HUMAN Homo sapiens Coagulation factor IX
P00740 FA9_HUMAN Homo sapiens Coagulation factor IX