PDB 5eap

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Overview

PDB Information

PDB	5EAP
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1). Getlik, M., Smil, D., Zepeda-Velazquez, C., Bolshan, Y., Poda, G., Wu, H., Dong, A., Kuznetsova, E., Marcellus, R., Senisterra, G., Dombrovski, L., Hajian, T., Kiyota, T., Schapira, M., Arrowsmith, C.H., Brown, P.J., Vedadi, M., Al-Awar, R. J. Med. Chem.
Header	Transcription/Transcription Inhibitor
Released	2015-10-16
Resolution	1.730
CATH Insert Date	15 Nov, 2015

PDB Images (3)

Image of CATH 5eap

5eap

PDB 5eap

Image of CATH 5eapA

5eapA

PDB Chain 5eapA

Image of CATH 5eapA00

5eapA00

CATH Domain 5eapA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	16 Nov, 2015	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5eapA00	24 Nov, 2015	2.130.10.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P61964	WDR5_HUMAN	Homo sapiens	WD repeat-containing protein 5