PDB Information

PDB5E0H
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceNorwalk virus
Primary Citation
Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies.
Weerawarna, P.M., Kim, Y., Galasiti Kankanamalage, A.C., Damalanka, V.C., Lushington, G.H., Alliston, K.R., Mehzabeen, N., Battaile, K.P., Lovell, S., Chang, K.O., Groutas, W.C.
Eur.J.Med.Chem.
HeaderProtease/Protease Inhibitor
Released2015-09-28
Resolution1.950
CATH Insert Date15 May, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5e0hA01 14 Jul, 2016 2.40.10.10 Assigned
5e0hA02 14 Jul, 2016 2.40.10.10 Assigned
5e0hB01 14 Jul, 2016 2.40.10.10 Assigned
5e0hB02 14 Jul, 2016 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q83883 POLG_NVN68 Norovirus Hu/1968/US Genome polyprotein
Q83883 POLG_NVN68 Norovirus Hu/1968/US Genome polyprotein