PDB 5dw1

PDB Information

PDB5DW1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
RVX-297- a novel BD2 selective inhibitor of BET bromodomains.
Kharenko, O.A., Gesner, E.M., Patel, R.G., Norek, K., White, A., Fontano, E., Suto, R.K., Young, P.R., McLure, K.G., Hansen, H.C.
Biochem.Biophys.Res.Commun.
HeaderProtein Binding/Inhibitor
Released2015-09-22
Resolution1.550
CATH Insert Date10 Jul, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
B 11 Jul, 2016 Chopped
C 11 Jul, 2016 Chopped
D 11 Jul, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5dw1A00 14 Jul, 2016 1.20.920.10 Assigned
5dw1B00 14 Jul, 2016 1.20.920.10 Assigned
5dw1C00 14 Jul, 2016 1.20.920.10 Assigned
5dw1D00 14 Jul, 2016 1.20.920.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2