PDB 5dw1

PDB Links
Overview

PDB Information

PDB	5DW1
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	RVX-297- a novel BD2 selective inhibitor of BET bromodomains. Kharenko, O.A., Gesner, E.M., Patel, R.G., Norek, K., White, A., Fontano, E., Suto, R.K., Young, P.R., McLure, K.G., Hansen, H.C. Biochem.Biophys.Res.Commun.
Header	Protein Binding/Inhibitor
Released	2015-09-22
Resolution	1.550
CATH Insert Date	10 Jul, 2016

PDB Images (9)

Image of CATH 5dw1

5dw1

PDB 5dw1

Image of CATH 5dw1A

5dw1A

PDB Chain 5dw1A

Image of CATH 5dw1B

5dw1B

PDB Chain 5dw1B

Image of CATH 5dw1C

5dw1C

PDB Chain 5dw1C

Image of CATH 5dw1D

5dw1D

PDB Chain 5dw1D

Image of CATH 5dw1A00

5dw1A00

CATH Domain 5dw1A00

Image of CATH 5dw1B00

5dw1B00

CATH Domain 5dw1B00

Image of CATH 5dw1C00

5dw1C00

CATH Domain 5dw1C00

Image of CATH 5dw1D00

5dw1D00

CATH Domain 5dw1D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped
C	11 Jul, 2016	Chopped
D	11 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dw1A00	14 Jul, 2016	1.20.920.10	Assigned
5dw1B00	14 Jul, 2016	1.20.920.10	Assigned
5dw1C00	14 Jul, 2016	1.20.920.10	Assigned
5dw1D00	14 Jul, 2016	1.20.920.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2