PDB 5dt2

PDB Links
Overview

PDB Information

PDB	5DT2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Chen, C., Zhu, H., Stauffer, F., Caravatti, G., Vollmer, S., Machauer, R., Holzer, P., Mobitz, H., Scheufler, C., Klumpp, M., Tiedt, R., Beyer, K.S., Calkins, K., Guthy, D., Kiffe, M., Zhang, J., Gaul, C. Acs Med.Chem.Lett.
Header	Transferase
Released	2015-09-17
Resolution	2.300
CATH Insert Date	10 Jul, 2016

PDB Images (7)

Image of CATH 5dt2

5dt2

PDB 5dt2

Image of CATH 5dt2A

5dt2A

PDB Chain 5dt2A

Image of CATH 5dt2B

5dt2B

PDB Chain 5dt2B

Image of CATH 5dt2A01

5dt2A01

CATH Domain 5dt2A01

Image of CATH 5dt2A02

5dt2A02

CATH Domain 5dt2A02

Image of CATH 5dt2B01

5dt2B01

CATH Domain 5dt2B01

Image of CATH 5dt2B02

5dt2B02

CATH Domain 5dt2B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dt2A01	14 Jul, 2016	1.10.260.60	Assigned
5dt2A02	14 Jul, 2016	3.40.50.150	Assigned
5dt2B01	14 Jul, 2016	1.10.260.60	Assigned
5dt2B02	14 Jul, 2016	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific