PDB 5dqc

PDB Links
Overview

PDB Information

PDB	5DQC
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes. Ghosh, A.K., Reddy, B.S., Yen, Y.C., Cardenas, E., Rao, K.V., Downs, D., Huang, X., Tang, J., Mesecar, A.D. Chem Sci
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-09-14
Resolution	2.470
CATH Insert Date	10 Apr, 2016

PDB Images (10)

Image of CATH 5dqc

5dqc

PDB 5dqc

Image of CATH 5dqcA

5dqcA

PDB Chain 5dqcA

Image of CATH 5dqcB

5dqcB

PDB Chain 5dqcB

Image of CATH 5dqcC

5dqcC

PDB Chain 5dqcC

Image of CATH 5dqcA01

5dqcA01

CATH Domain 5dqcA01

Image of CATH 5dqcA02

5dqcA02

CATH Domain 5dqcA02

Image of CATH 5dqcB01

5dqcB01

CATH Domain 5dqcB01

Image of CATH 5dqcB02

5dqcB02

CATH Domain 5dqcB02

Image of CATH 5dqcC01

5dqcC01

CATH Domain 5dqcC01

Image of CATH 5dqcC02

5dqcC02

CATH Domain 5dqcC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped
C	11 Apr, 2016	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dqcA01	07 May, 2016	2.40.70.10	Assigned
5dqcA02	07 May, 2016	2.40.70.10	Assigned
5dqcB01	07 May, 2016	2.40.70.10	Assigned
5dqcB02	07 May, 2016	2.40.70.10	Assigned
5dqcC01	07 May, 2016	2.40.70.10	Assigned
5dqcC02	07 May, 2016	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1