PDB 5dh4

PDB Links
Overview

PDB Information

PDB	5DH4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Raheem, I.T., Schreier, J.D., Fuerst, J., Gantert, L., Hostetler, E.D., Huszar, S., Joshi, A., Kandebo, M., Kim, S.H., Li, J., Ma, B., McGaughey, G., Sharma, S., Shipe, W.D., Uslaner, J., Vandeveer, G.H., Yan, Y., Renger, J.J., Smith, S.M., Coleman, P.J., Cox, C.D. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-08-29
Resolution	2.200
CATH Insert Date	10 Apr, 2016

PDB Images (5)

Image of CATH 5dh4

5dh4

PDB 5dh4

Image of CATH 5dh4A

5dh4A

PDB Chain 5dh4A

Image of CATH 5dh4B

5dh4B

PDB Chain 5dh4B

Image of CATH 5dh4A00

5dh4A00

CATH Domain 5dh4A00

Image of CATH 5dh4B00

5dh4B00

CATH Domain 5dh4B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dh4A00	07 May, 2016	1.10.1300.10	Assigned
5dh4B00	07 May, 2016	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A