PDB 5czx

PDB Information

PDB5CZX
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Bernasconi-Elias, P., Hu, T., Jenkins, D., Firestone, B., Gans, S., Kurth, E., Capodieci, P., Deplazes-Lauber, J., Petropoulos, K., Thiel, P., Ponsel, D., Hee Choi, S., LeMotte, P., London, A., Goetcshkes, M., Nolin, E., Jones, M.D., Slocum, K., Kluk, M.J., Weinstock, D.M., Christodoulou, A., Weinberg, O., Jaehrling, J., Ettenberg, S.A., Buckler, A., Blacklow, S.C., Aster, J.C., Fryer, C.J.
Oncogene
HeaderImmune System
Released2015-08-01
Resolution2.100
CATH Insert Date19 Jun, 2016

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2016 Chopped
B 20 Jun, 2016 Chopped
C 20 Jun, 2016 Chopped
D 20 Jun, 2016 Chopped
H 20 Jun, 2016 Chopped
L 20 Jun, 2016 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5czxA01 13 Jul, 2016 3.30.300.320 Assigned
5czxA02 13 Jul, 2016 3.30.70.3310 Assigned
5czxB01 13 Jul, 2016 3.30.300.320 Assigned
5czxB02 13 Jul, 2016 3.30.70.3310 Assigned
5czxC01 13 Jul, 2016 2.60.40.10 Assigned
5czxC02 13 Jul, 2016 2.60.40.10 Assigned
5czxD01 13 Jul, 2016 2.60.40.10 Assigned
5czxD02 13 Jul, 2016 2.60.40.10 Assigned
5czxH01 13 Jul, 2016 2.60.40.10 Assigned
5czxH02 13 Jul, 2016 2.60.40.10 Assigned
5czxL01 13 Jul, 2016 2.60.40.10 Assigned
5czxL02 13 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UM47 NOTC3_HUMAN Homo sapiens Neurogenic locus notch homolog protein 3
Q9UM47 NOTC3_HUMAN Homo sapiens Neurogenic locus notch homolog protein 3