PDB Information

PDB5CS3
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris CBS 7435
Gene SourceHomo sapiens
Primary Citation
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.
Sigurdardottir, A.G., Winter, A., Sobkowicz, A., Fragai, M., Chirgadze, D., Ascher, D.B., Blundell, T.L., Gherardi, E.
Chem Sci
HeaderHormone
Released2015-07-23
Resolution2.500
CATH Insert Date30 Aug, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 31 Aug, 2015 Chopped
B 31 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5cs3A01 03 Sep, 2015 3.50.4.10 Assigned
5cs3A02 03 Sep, 2015 2.40.20.10 Assigned
5cs3B01 03 Sep, 2015 3.50.4.10 Assigned
5cs3B02 03 Sep, 2015 2.40.20.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14210 HGF_HUMAN Homo sapiens Hepatocyte growth factor
P14210 HGF_HUMAN Homo sapiens Hepatocyte growth factor