PDB Information

PDB5COE
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris
Gene SourceHomo sapiens
Primary Citation
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.
Sigurdardottir, A.G., Winter, A., Sobkowicz, A., Fragai, M., Chirgadze, D., Ascher, D.B., Blundell, T.L., Gherardi, E.
Chem Sci
HeaderHormone
Released2015-07-20
Resolution2.180
CATH Insert Date30 Aug, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 31 Aug, 2015 Chopped
B 31 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5coeA01 02 Sep, 2015 3.50.4.10 Assigned
5coeA02 02 Sep, 2015 2.40.20.10 Assigned
5coeB01 03 Sep, 2015 3.50.4.10 Assigned
5coeB02 03 Sep, 2015 2.40.20.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14210 HGF_HUMAN Homo sapiens Hepatocyte growth factor
P14210 HGF_HUMAN Homo sapiens Hepatocyte growth factor