PDB 5clm

PDB Information

PDB5CLM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
1,4-Oxazine beta-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads.
Rombouts, F.J., Tresadern, G., Delgado, O., Martinez-Lamenca, C., Van Gool, M., Garcia-Molina, A., Alonso de Diego, S.A., Oehlrich, D., Prokopcova, H., Alonso, J.M., Austin, N., Borghys, H., Van Brandt, S., Surkyn, M., De Cleyn, M., Vos, A., Alexander, R., Macdonald, G., Moechars, D., Gijsen, H., Trabanco, A.A.
J.Med.Chem.
HeaderHydrolase
Released2015-07-16
Resolution2.610
CATH Insert Date04 Oct, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Oct, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5clmA01 31 Oct, 2015 2.40.70.10 Assigned
5clmA02 31 Oct, 2015 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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