PDB 5cf5

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Overview

PDB Information

PDB	5CF5
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors. Hart, A.C., Schroeder, G.M., Wan, H., Grebinski, J., Inghrim, J., Kempson, J., Guo, J., Pitts, W.J., Tokarski, J.S., Sack, J.S., Khan, J.A., Lippy, J., Lorenzi, M.V., You, D., McDevitt, T., Vuppugalla, R., Zhang, Y., Lombardo, L.J., Trainor, G.L., Purandare, A.V. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-07-08
Resolution	2.450
CATH Insert Date	06 Sep, 2015

PDB Images (7)

Image of CATH 5cf5

5cf5

PDB 5cf5

Image of CATH 5cf5A

5cf5A

PDB Chain 5cf5A

Image of CATH 5cf5B

5cf5B

PDB Chain 5cf5B

Image of CATH 5cf5A01

5cf5A01

CATH Domain 5cf5A01

Image of CATH 5cf5A02

5cf5A02

CATH Domain 5cf5A02

Image of CATH 5cf5B01

5cf5B01

CATH Domain 5cf5B01

Image of CATH 5cf5B02

5cf5B02

CATH Domain 5cf5B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	07 Sep, 2015	Chopped
B	07 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5cf5A01	11 Sep, 2015	3.30.200.20	Assigned
5cf5A02	11 Sep, 2015	1.10.510.10	Assigned
5cf5B01	30 Sep, 2015	3.30.200.20	Assigned
5cf5B02	30 Sep, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2