PDB Information

PDB5CDQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus (strain N315)
Primary Citation
Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Chan, P.F., Srikannathasan, V., Huang, J., Cui, H., Fosberry, A.P., Gu, M., Hann, M.M., Hibbs, M., Homes, P., Ingraham, K., Pizzollo, J., Shen, C., Shillings, A.J., Spitzfaden, C.E., Tanner, R., Theobald, A.J., Stavenger, R.A., Bax, B.D., Gwynn, M.N.
Nat Commun
HeaderHydrolase
Released2015-07-04
Resolution2.950
CATH Insert Date27 Dec, 2015

PDB Images (21)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 28 Dec, 2015 Chopped
B 28 Dec, 2015 Chopped
C 28 Dec, 2015 Chopped
D 28 Dec, 2015 Chopped
E 28 Dec, 2015 Rejected
F 28 Dec, 2015 Rejected
R 28 Dec, 2015 Chopped
S 28 Dec, 2015 Chopped
T 28 Dec, 2015 Chopped
U 28 Dec, 2015 Chopped
V 28 Dec, 2015 Rejected
W 28 Dec, 2015 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5cdqA00 05 Jan, 2016 Holding pen
5cdqB01 23 Jan, 2017 Holding pen
5cdqC00 05 Jan, 2016 Holding pen
5cdqD01 23 Jan, 2017 Holding pen
5cdqR00 05 Jan, 2016 Holding pen
5cdqS01 23 Jan, 2017 Holding pen
5cdqT00 05 Jan, 2016 Holding pen
5cdqU01 23 Jan, 2017 Holding pen

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B