PDB 5c9c

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Overview

PDB Information

PDB	5C9C
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers. Peng, S.B., Henry, J.R., Kaufman, M.D., Lu, W.P., Smith, B.D., Vogeti, S., Rutkoski, T.J., Wise, S., Chun, L., Zhang, Y., Van Horn, R.D., Yin, T., Zhang, X., Yadav, V., Chen, S.H., Gong, X., Ma, X., Webster, Y., Buchanan, S., Mochalkin, I., Huber, L., Kays, L., Donoho, G.P., Walgren, J., McCann, D., Patel, P., Conti, I., Plowman, G.D., Starling, J.J., Flynn, D.L. Cancer Cell
Header	Transferase/Transferase Inhibitor
Released	2015-06-26
Resolution	2.700
CATH Insert Date	26 Jul, 2015

PDB Images (7)

Image of CATH 5c9c

5c9c

PDB 5c9c

Image of CATH 5c9cA

5c9cA

PDB Chain 5c9cA

Image of CATH 5c9cB

5c9cB

PDB Chain 5c9cB

Image of CATH 5c9cA01

5c9cA01

CATH Domain 5c9cA01

Image of CATH 5c9cA02

5c9cA02

CATH Domain 5c9cA02

Image of CATH 5c9cB01

5c9cB01

CATH Domain 5c9cB01

Image of CATH 5c9cB02

5c9cB02

CATH Domain 5c9cB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	27 Jul, 2015	Chopped
B	27 Jul, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5c9cA01	30 Jul, 2015	3.30.200.20	Assigned
5c9cA02	30 Jul, 2015	1.10.510.10	Assigned
5c9cB01	30 Jul, 2015	3.30.200.20	Assigned
5c9cB02	30 Jul, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf