PDB 5c5r

PDB Links
Overview

PDB Information

PDB	5C5R
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors. de Vicente, J., Tivitmahaisoon, P., Berry, P., Bolin, D.R., Carvajal, D., He, W., Huang, K.S., Janson, C., Liang, L., Lukacs, C., Petersen, A., Qian, H., Yi, L., Zhuang, Y., Hermann, J.C. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-06-21
Resolution	1.550
CATH Insert Date	30 Aug, 2015

PDB Images (9)

Image of CATH 5c5r

5c5r

PDB 5c5r

Image of CATH 5c5rA

5c5rA

PDB Chain 5c5rA

Image of CATH 5c5rB

5c5rB

PDB Chain 5c5rB

Image of CATH 5c5rC

5c5rC

PDB Chain 5c5rC

Image of CATH 5c5rD

5c5rD

PDB Chain 5c5rD

Image of CATH 5c5rA00

5c5rA00

CATH Domain 5c5rA00

Image of CATH 5c5rB00

5c5rB00

CATH Domain 5c5rB00

Image of CATH 5c5rC00

5c5rC00

CATH Domain 5c5rC00

Image of CATH 5c5rD00

5c5rD00

CATH Domain 5c5rD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	31 Aug, 2015	Chopped
B	31 Aug, 2015	Chopped
C	31 Aug, 2015	Chopped
D	31 Aug, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5c5rA00	03 Sep, 2015	3.90.228.10	Assigned
5c5rB00	03 Sep, 2015	3.90.228.10	Assigned
5c5rC00	03 Sep, 2015	6.20.320.10	Assigned
5c5rD00	03 Sep, 2015	6.20.320.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2