PDB Information

PDB5C37
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of a Series of Bioavailable Fatty Acid Synthase (FASN) KR Domain Inhibitors for Cancer Therapy
Lu, T., Schubert, C., Cummings, M.D., Bignan, G., Connolly, P., Smans, K., Ludovici, D., Parker, M., Meyer, C., Rocaboy, C., Alexander, R., Grasberger, B., De Breucker, S., Esser, N., Fraiponts, E., Gilissen, R., Janssens, B., Peeters, D., Van Nuffel, L., Vermeulen, P., Bischoff, J., Meerpoel, L.
to be published
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2015-06-17
Resolution2.300
CATH Insert Date10 Jul, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
C 11 Jul, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5c37A01 13 Jul, 2016 Holding pen
5c37A02 13 Jul, 2016 3.40.50.720 Assigned
5c37C01 13 Jul, 2016 Holding pen
5c37C02 13 Jul, 2016 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase