PDB 5c29

PDB Links
Overview

PDB Information

PDB	5C29
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis. Shipe, W.D., Sharik, S.S., Barrow, J.C., McGaughey, G.B., Theberge, C.R., Uslaner, J.M., Yan, Y., Renger, J.J., Smith, S.M., Coleman, P.J., Cox, C.D. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-06-15
Resolution	2.050
CATH Insert Date	04 Oct, 2015

PDB Images (5)

Image of CATH 5c29

5c29

PDB 5c29

Image of CATH 5c29A

5c29A

PDB Chain 5c29A

Image of CATH 5c29B

5c29B

PDB Chain 5c29B

Image of CATH 5c29A00

5c29A00

CATH Domain 5c29A00

Image of CATH 5c29B00

5c29B00

CATH Domain 5c29B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Oct, 2015	Chopped
B	05 Oct, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5c29A00	01 Nov, 2015	1.10.1300.10	Assigned
5c29B00	31 Oct, 2015	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A