PDB 5c25

PDB Information

PDB5C25
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 group M subtype B (isolate BH10)
Primary Citation
Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase.
Lee, W.G., Frey, K.M., Gallardo-Macias, R., Spasov, K.A., Chan, A.H., Anderson, K.S., Jorgensen, W.L.
Bioorg.Med.Chem.Lett.
HeaderTransferase, Hydrolase/Inhibitor
Released2015-06-15
Resolution2.840
CATH Insert Date16 Aug, 2015

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
5c25A01 24 Aug, 2015 3.10.10.10 Assigned
5c25A02 24 Aug, 2015 3.30.70.270 Assigned
5c25A03 24 Aug, 2015 3.30.70.270 Assigned
5c25A04 24 Aug, 2015 3.30.70.270 Assigned
5c25A05 24 Aug, 2015 3.30.420.10 Assigned
5c25B01 24 Aug, 2015 3.10.10.10 Assigned
5c25B02 24 Aug, 2015 3.30.70.270 Assigned
5c25B03 24 Aug, 2015 3.30.70.270 Assigned
5c25B04 24 Aug, 2015 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein