PDB 5bpy

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Overview

PDB Information

PDB	5BPY
Method	X-RAY DIFFRACTION
Host Organism	Baculovirus expression vector pFastBac1-HM
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2). Liu, Q., Batt, D.G., Lippy, J.S., Surti, N., Tebben, A.J., Muckelbauer, J.K., Chen, L., An, Y., Chang, C., Pokross, M., Yang, Z., Wang, H., Burke, J.R., Carter, P.H., Tino, J.A. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-05-28
Resolution	2.310
CATH Insert Date	04 Oct, 2015

PDB Images (7)

Image of CATH 5bpy

5bpy

PDB 5bpy

Image of CATH 5bpyA

5bpyA

PDB Chain 5bpyA

Image of CATH 5bpyB

5bpyB

PDB Chain 5bpyB

Image of CATH 5bpyA01

5bpyA01

CATH Domain 5bpyA01

Image of CATH 5bpyA02

5bpyA02

CATH Domain 5bpyA02

Image of CATH 5bpyB01

5bpyB01

CATH Domain 5bpyB01

Image of CATH 5bpyB02

5bpyB02

CATH Domain 5bpyB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Oct, 2015	Chopped
B	05 Oct, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5bpyA01	01 Nov, 2015	3.30.200.20	Assigned
5bpyA02	01 Nov, 2015	1.10.510.10	Assigned
5bpyB01	01 Nov, 2015	3.30.200.20	Assigned
5bpyB02	01 Nov, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q06187	BTK_HUMAN	Homo sapiens	Tyrosine-protein kinase BTK
Q06187	BTK_HUMAN	Homo sapiens	Tyrosine-protein kinase BTK