PDB 5b5t
PDB Information
| PDB | 5B5T |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Escherichia coli (strain K12) |
| Primary Citation | Phosphonate-based irreversible inhibitors of human gamma-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity
Bioorg.Med.Chem.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2016-05-18 |
| Resolution | 1.700 |
| CATH Insert Date | 09 Oct, 2016 |
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 10 Oct, 2016 | Chopped |
| B | 10 Oct, 2016 | Chopped |
| C | 10 Oct, 2016 | Chopped |
| D | 10 Oct, 2016 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5b5tA01 | 14 Oct, 2016 | Holding pen | |
| 5b5tA02 | 14 Oct, 2016 | 1.10.246.130 | Assigned |
| 5b5tB00 | 14 Oct, 2016 | Holding pen | |
| 5b5tC01 | 13 Oct, 2016 | Holding pen | |
| 5b5tC02 | 13 Oct, 2016 | 1.10.246.130 | Assigned |
| 5b5tD00 | 13 Oct, 2016 | Holding pen |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P18956 | GGT_ECOLI | Escherichia coli K-12 | Glutathione hydrolase proenzyme |
| P18956 | GGT_ECOLI | Escherichia coli K-12 | Glutathione hydrolase proenzyme |
| P18956 | GGT_ECOLI | Escherichia coli K-12 | Glutathione hydrolase proenzyme |
| P18956 | GGT_ECOLI | Escherichia coli K-12 | Glutathione hydrolase proenzyme |
