PDB 5axp

PDB Links
Overview

PDB Information

PDB	5AXP
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of a novel 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor Yoshikawa, M., Kamisaki, H., Kunitomo, J., Oki, H., Kokubo, H., Suzuki, A., Ikemoto, T., Nakashima, K., Kamiguchi, N., Harada, A., Kimura, H., Taniguchi, T. Bioorg.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-07-31
Resolution	1.950
CATH Insert Date	29 Nov, 2015

PDB Images (5)

Image of CATH 5axp

5axp

PDB 5axp

Image of CATH 5axpA

5axpA

PDB Chain 5axpA

Image of CATH 5axpB

5axpB

PDB Chain 5axpB

Image of CATH 5axpA00

5axpA00

CATH Domain 5axpA00

Image of CATH 5axpB00

5axpB00

CATH Domain 5axpB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 Nov, 2015	Chopped
B	30 Nov, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5axpA00	03 Dec, 2015	1.10.1300.10	Assigned
5axpB00	03 Dec, 2015	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A