PDB 5aab

PDB Information

PDB5AAB
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F.
Shaw, A.T., Friboulet, L., Leshchiner, I., Gainor, J.F., Bergqvist, S., Brooun, A., Burke, B.J., Deng, Y., Liu, W., Dardaei, L., Frias, R.L., Schultz, K.R., Logan, J., James, L.P., Smeal, T., Timofeevski, S., Katayama, R., Iafrate, A.J., Le, L., Mctigue, M., Getz, G., Johnson, T.W., Engelman, J.A.
N.Engl.J.Med.
HeaderTransferase
Released2015-07-23
Resolution2.200
CATH Insert Date19 Jun, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5aabA01 13 May, 2019 3.30.200.20 Assigned
5aabA02 13 May, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor