PDB 5a0b

PDB Information

PDB5A0B
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases.
von Nussbaum, F., Li, V.M., Allerheiligen, S., Anlauf, S., Barfacker, L., Bechem, M., Delbeck, M., Fitzgerald, M.F., Gerisch, M., Gielen-Haertwig, H., Haning, H., Karthaus, D., Lang, D., Lustig, K., Meibom, D., Mittendorf, J., Rosentreter, U., Schafer, M., Schafer, S., Schamberger, J., Telan, L.A., Tersteegen, A.
ChemMedChem
HeaderHydrolase
Released2015-04-17
Resolution2.230
CATH Insert Date30 Aug, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Aug, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5a0bA01 03 Sep, 2015 2.40.10.10 Assigned
5a0bA02 03 Sep, 2015 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08246 ELNE_HUMAN Homo sapiens Neutrophil elastase