PDB 4zyc

PDB Links
Overview

PDB Information

PDB	4ZYC
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode. Gessier, F., Kallen, J., Jacoby, E., Chene, P., Stachyra-Valat, T., Ruetz, S., Jeay, S., Holzer, P., Masuya, K., Furet, P. Bioorg.Med.Chem.Lett.
Header	Ligase
Released	2015-05-21
Resolution	1.950
CATH Insert Date	16 Aug, 2015

PDB Images (7)

Image of CATH 4zyc

4zyc

PDB 4zyc

Image of CATH 4zycA

4zycA

PDB Chain 4zycA

Image of CATH 4zycB

4zycB

PDB Chain 4zycB

Image of CATH 4zycC

4zycC

PDB Chain 4zycC

Image of CATH 4zycA00

4zycA00

CATH Domain 4zycA00

Image of CATH 4zycB00

4zycB00

CATH Domain 4zycB00

Image of CATH 4zycC00

4zycC00

CATH Domain 4zycC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	17 Aug, 2015	Chopped
B	17 Aug, 2015	Chopped
C	17 Aug, 2015	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zycA00	20 Mar, 2016	1.10.245.10	Assigned
4zycB00	20 Mar, 2016	1.10.245.10	Assigned
4zycC00	20 Mar, 2016	1.10.245.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2