PDB 4zy2

PDB Links
Overview

PDB Information

PDB	4ZY2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Plasmodium falciparum FcB1/Columbia
Primary Citation	Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J. Eur.J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-05-21
Resolution	2.100
CATH Insert Date	17 Apr, 2016

PDB Images (37)

4zy2

PDB 4zy2

4zy2A

PDB Chain 4zy2A

4zy2B

PDB Chain 4zy2B

4zy2C

PDB Chain 4zy2C

4zy2D

PDB Chain 4zy2D

4zy2E

PDB Chain 4zy2E

4zy2F

PDB Chain 4zy2F

4zy2G

PDB Chain 4zy2G

4zy2H

PDB Chain 4zy2H

4zy2I

PDB Chain 4zy2I

4zy2J

PDB Chain 4zy2J

4zy2K

PDB Chain 4zy2K

4zy2L

PDB Chain 4zy2L

4zy2A01

CATH Domain 4zy2A01

4zy2A02

CATH Domain 4zy2A02

4zy2B01

CATH Domain 4zy2B01

4zy2B02

CATH Domain 4zy2B02

4zy2C01

CATH Domain 4zy2C01

4zy2C02

CATH Domain 4zy2C02

4zy2D01

CATH Domain 4zy2D01

4zy2D02

CATH Domain 4zy2D02

4zy2E01

CATH Domain 4zy2E01

4zy2E02

CATH Domain 4zy2E02

4zy2F01

CATH Domain 4zy2F01

4zy2F02

CATH Domain 4zy2F02

4zy2G01

CATH Domain 4zy2G01

4zy2G02

CATH Domain 4zy2G02

4zy2H01

CATH Domain 4zy2H01

4zy2H02

CATH Domain 4zy2H02

4zy2I01

CATH Domain 4zy2I01

4zy2I02

CATH Domain 4zy2I02

4zy2J01

CATH Domain 4zy2J01

4zy2J02

CATH Domain 4zy2J02

4zy2K01

CATH Domain 4zy2K01

4zy2K02

CATH Domain 4zy2K02

4zy2L01

CATH Domain 4zy2L01

4zy2L02

CATH Domain 4zy2L02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	18 Apr, 2016	Chopped
B	18 Apr, 2016	Chopped
C	18 Apr, 2016	Chopped
D	18 Apr, 2016	Chopped
E	18 Apr, 2016	Chopped
F	18 Apr, 2016	Chopped
G	18 Apr, 2016	Chopped
H	18 Apr, 2016	Chopped
I	18 Apr, 2016	Chopped
J	18 Apr, 2016	Chopped
K	18 Apr, 2016	Chopped
L	18 Apr, 2016	Chopped

CATH Domains (24)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zy2A01	03 May, 2016	3.40.220.10	Assigned
4zy2A02	03 May, 2016	3.40.630.10	Assigned
4zy2B01	03 May, 2016	3.40.220.10	Assigned
4zy2B02	03 May, 2016	3.40.630.10	Assigned
4zy2C01	03 May, 2016	3.40.220.10	Assigned
4zy2C02	03 May, 2016	3.40.630.10	Assigned
4zy2D01	03 May, 2016	3.40.220.10	Assigned
4zy2D02	03 May, 2016	3.40.630.10	Assigned
4zy2E01	03 May, 2016	3.40.220.10	Assigned
4zy2E02	03 May, 2016	3.40.630.10	Assigned
4zy2F01	03 May, 2016	3.40.220.10	Assigned
4zy2F02	03 May, 2016	3.40.630.10	Assigned
4zy2G01	03 May, 2016	3.40.220.10	Assigned
4zy2G02	03 May, 2016	3.40.630.10	Assigned
4zy2H01	03 May, 2016	3.40.220.10	Assigned
4zy2H02	03 May, 2016	3.40.630.10	Assigned
4zy2I01	03 May, 2016	3.40.220.10	Assigned
4zy2I02	03 May, 2016	3.40.630.10	Assigned
4zy2J01	03 May, 2016	3.40.220.10	Assigned
4zy2J02	03 May, 2016	3.40.630.10	Assigned
4zy2K01	03 May, 2016	3.40.220.10	Assigned
4zy2K02	03 May, 2016	3.40.630.10	Assigned
4zy2L01	03 May, 2016	3.40.220.10	Assigned
4zy2L02	03 May, 2016	3.40.630.10	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein
A0A0L7M119	A0A0L7M119_PLAF4	Plasmodium falciparum Dd2	Uncharacterized protein