PDB 4zy1

PDB Information

PDB4ZY1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum FcB1/Columbia
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-21
Resolution2.500
CATH Insert Date10 Apr, 2016

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped
E 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped
G 11 Apr, 2016 Chopped
H 11 Apr, 2016 Chopped
I 11 Apr, 2016 Chopped
J 11 Apr, 2016 Chopped
K 11 Apr, 2016 Chopped
L 11 Apr, 2016 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4zy1A01 03 May, 2016 3.40.220.10 Assigned
4zy1A02 03 May, 2016 3.40.630.10 Assigned
4zy1B01 03 May, 2016 3.40.220.10 Assigned
4zy1B02 03 May, 2016 3.40.630.10 Assigned
4zy1C01 03 May, 2016 3.40.220.10 Assigned
4zy1C02 03 May, 2016 3.40.630.10 Assigned
4zy1D01 03 May, 2016 3.40.220.10 Assigned
4zy1D02 03 May, 2016 3.40.630.10 Assigned
4zy1E01 03 May, 2016 3.40.220.10 Assigned
4zy1E02 03 May, 2016 3.40.630.10 Assigned
4zy1F01 03 May, 2016 3.40.220.10 Assigned
4zy1F02 03 May, 2016 3.40.630.10 Assigned
4zy1G01 03 May, 2016 3.40.220.10 Assigned
4zy1G02 03 May, 2016 3.40.630.10 Assigned
4zy1H01 03 May, 2016 3.40.220.10 Assigned
4zy1H02 03 May, 2016 3.40.630.10 Assigned
4zy1I01 03 May, 2016 3.40.220.10 Assigned
4zy1I02 03 May, 2016 3.40.630.10 Assigned
4zy1J01 03 May, 2016 3.40.220.10 Assigned
4zy1J02 03 May, 2016 3.40.630.10 Assigned
4zy1K01 03 May, 2016 3.40.220.10 Assigned
4zy1K02 03 May, 2016 3.40.630.10 Assigned
4zy1L01 03 May, 2016 3.40.220.10 Assigned
4zy1L02 03 May, 2016 3.40.630.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
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