PDB Information

PDB4ZX3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-20
Resolution2.000
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4zx3A01 03 May, 2016 2.60.40.1730 Assigned
4zx3A02 03 May, 2016 1.10.1740.60 Assigned
4zx3A03 03 May, 2016 1.10.390.10 Assigned
4zx3A04 03 May, 2016 2.60.40.1840 Assigned
4zx3A05 03 May, 2016 1.25.50.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O96935 AMP1_PLAFQ Plasmodium falciparum FcB1/Columbia M1 family aminopeptidase