PDB 4zx2

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PDB Information

PDB	4ZX2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C. Chattopadhyay, D., Swingle, M.R., Salter, E.A., Wood, E., D'Arcy, B., Zivanov, C., Abney, K., Musiyenko, A., Rusin, S.F., Kettenbach, A., Yet, L., Schroeder, C.E., Golden, J.E., Dunham, W.H., Gingras, A.C., Banerjee, S., Forbes, D., Wierzbicki, A., Honkanen, R.E. Biochem. Pharmacol.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-05-20
Resolution	1.230
CATH Insert Date	08 May, 2016

PDB Images (3)

Image of CATH 4zx2

4zx2

PDB 4zx2

Image of CATH 4zx2A

4zx2A

PDB Chain 4zx2A

Image of CATH 4zx2A00

4zx2A00

CATH Domain 4zx2A00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	09 May, 2016	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zx2A00	22 Nov, 2016	3.60.21.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P53041	PPP5_HUMAN	Homo sapiens	Serine/threonine-protein phosphatase 5