PDB 4zo5

PDB Links
Overview

PDB Information

PDB	4ZO5
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors. Cox, C.D., Hostetler, E.D., Flores, B.A., Evelhoch, J.L., Fan, H., Gantert, L., Holahan, M., Eng, W., Joshi, A., McGaughey, G., Meng, X., Purcell, M., Raheem, I.T., Riffel, K., Yan, Y., Renger, J.J., Smith, S.M., Coleman, P.J. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-05-06
Resolution	2.500
CATH Insert Date	30 Aug, 2015

PDB Images (5)

Image of CATH 4zo5

4zo5

PDB 4zo5

Image of CATH 4zo5A

4zo5A

PDB Chain 4zo5A

Image of CATH 4zo5B

4zo5B

PDB Chain 4zo5B

Image of CATH 4zo5A00

4zo5A00

CATH Domain 4zo5A00

Image of CATH 4zo5B00

4zo5B00

CATH Domain 4zo5B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	31 Aug, 2015	Chopped
B	31 Aug, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zo5A00	02 Sep, 2015	1.10.1300.10	Assigned
4zo5B00	03 Sep, 2015	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A