PDB Information

PDB4ZN9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands.
Zheng, Y., Zhu, M., Srinivasan, S., Nwachukwu, J.C., Cavett, V., Min, J., Carlson, K.E., Wang, P., Dong, C., Katzenellenbogen, J.A., Nettles, K.W., Zhou, H.B.
Chemmedchem
HeaderTranscription
Released2015-05-04
Resolution2.220
CATH Insert Date20 Sep, 2015

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Sep, 2015 Chopped
B 21 Sep, 2015 Chopped
C 21 Sep, 2015 Rejected
D 21 Sep, 2015 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4zn9A00 30 Sep, 2015 1.10.565.10 Assigned
4zn9B00 30 Sep, 2015 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor