PDB 4zim

PDB Links
Overview

PDB Information

PDB	4ZIM
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors. Zimmermann, K., Sang, X., Mastalerz, H.A., Johnson, W.L., Zhang, G., Liu, Q., Batt, D., Lombardo, L.J., Vyas, D., Trainor, G.L., Tokarski, J.S., Lorenzi, M.V., You, D., Gottardis, M.M., Lippy, J., Khan, J., Sack, J.S., Purandare, A.V. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-04-28
Resolution	2.650
CATH Insert Date	28 Jun, 2015

PDB Images (7)

Image of CATH 4zim

4zim

PDB 4zim

Image of CATH 4zimA

4zimA

PDB Chain 4zimA

Image of CATH 4zimB

4zimB

PDB Chain 4zimB

Image of CATH 4zimA01

4zimA01

CATH Domain 4zimA01

Image of CATH 4zimA02

4zimA02

CATH Domain 4zimA02

Image of CATH 4zimB01

4zimB01

CATH Domain 4zimB01

Image of CATH 4zimB02

4zimB02

CATH Domain 4zimB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zimA01	27 Jul, 2015	3.30.200.20	Assigned
4zimA02	27 Jul, 2015	1.10.510.10	Assigned
4zimB01	27 Jul, 2015	3.30.200.20	Assigned
4zimB02	27 Jul, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2