PDB 4zgk

PDB Information

PDB4ZGK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction.
Surmiak, E., Twarda-Clapa, A., Zak, K.M., Musielak, B., Tomala, M.D., Kubica, K., Grudnik, P., Madej, M., Jablonski, M., Potempa, J., Kalinowska-Tluscik, J., Domling, A., Dubin, G., Holak, T.A.
ACS Chem. Biol.
HeaderLigase
Released2015-04-23
Resolution2.000
CATH Insert Date06 Nov, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped
B 07 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4zgkA00 10 Nov, 2016 1.10.245.10 Assigned
4zgkB00 10 Nov, 2016 1.10.245.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
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