PDB 4zfi

PDB Links
Overview

PDB Information

PDB	4ZFI
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction. Surmiak, E., Twarda-Clapa, A., Zak, K.M., Musielak, B., Tomala, M.D., Kubica, K., Grudnik, P., Madej, M., Jablonski, M., Potempa, J., Kalinowska-Tluscik, J., Domling, A., Dubin, G., Holak, T.A. ACS Chem. Biol.
Header	Ligase
Released	2015-04-21
Resolution	2.000
CATH Insert Date	06 Nov, 2016

PDB Images (9)

Image of CATH 4zfi

4zfi

PDB 4zfi

Image of CATH 4zfiA

4zfiA

PDB Chain 4zfiA

Image of CATH 4zfiB

4zfiB

PDB Chain 4zfiB

Image of CATH 4zfiC

4zfiC

PDB Chain 4zfiC

Image of CATH 4zfiD

4zfiD

PDB Chain 4zfiD

Image of CATH 4zfiA00

4zfiA00

CATH Domain 4zfiA00

Image of CATH 4zfiB00

4zfiB00

CATH Domain 4zfiB00

Image of CATH 4zfiC00

4zfiC00

CATH Domain 4zfiC00

Image of CATH 4zfiD00

4zfiD00

CATH Domain 4zfiD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	07 Nov, 2016	Chopped
B	07 Nov, 2016	Chopped
C	07 Nov, 2016	Chopped
D	07 Nov, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zfiA00	10 Nov, 2016	1.10.245.10	Assigned
4zfiB00	10 Nov, 2016	1.10.245.10	Assigned
4zfiC00	10 Nov, 2016	1.10.245.10	Assigned
4zfiD00	09 Nov, 2016	1.10.245.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2