PDB 4zdi

PDB Links
Overview

PDB Information

PDB	4ZDI
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Primary Citation	Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. Mori, G., Chiarelli, L.R., Esposito, M., Makarov, V., Bellinzoni, M., Hartkoorn, R.C., Degiacomi, G., Boldrin, F., Ekins, S., de Jesus Lopes Ribeiro, A.L., Marino, L.B., Centarova, I., Svetlikova, Z., Blasko, J., Kazakova, E., Lepioshkin, A., Barilone, N., Zanoni, G., Porta, A., Fondi, M., Fani, R., Baulard, A.R., Mikusova, K., Alzari, P.M., Manganelli, R., de Carvalho, L.P., Riccardi, G., Cole, S.T., Pasca, M.R. Chem.Biol.
Header	Ligase
Released	2015-04-17
Resolution	3.520
CATH Insert Date	16 Aug, 2015

PDB Images (25)

4zdi

PDB 4zdi

4zdiA

PDB Chain 4zdiA

4zdiB

PDB Chain 4zdiB

4zdiC

PDB Chain 4zdiC

4zdiD

PDB Chain 4zdiD

4zdiE

PDB Chain 4zdiE

4zdiF

PDB Chain 4zdiF

4zdiG

PDB Chain 4zdiG

4zdiH

PDB Chain 4zdiH

4zdiA01

CATH Domain 4zdiA01

4zdiA02

CATH Domain 4zdiA02

4zdiB01

CATH Domain 4zdiB01

4zdiB02

CATH Domain 4zdiB02

4zdiC01

CATH Domain 4zdiC01

4zdiC02

CATH Domain 4zdiC02

4zdiD01

CATH Domain 4zdiD01

4zdiD02

CATH Domain 4zdiD02

4zdiE01

CATH Domain 4zdiE01

4zdiE02

CATH Domain 4zdiE02

4zdiF01

CATH Domain 4zdiF01

4zdiF02

CATH Domain 4zdiF02

4zdiG01

CATH Domain 4zdiG01

4zdiG02

CATH Domain 4zdiG02

4zdiH01

CATH Domain 4zdiH01

4zdiH02

CATH Domain 4zdiH02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	17 Aug, 2015	Chopped
B	17 Aug, 2015	Chopped
C	17 Aug, 2015	Chopped
D	17 Aug, 2015	Chopped
E	17 Aug, 2015	Chopped
F	17 Aug, 2015	Chopped
G	17 Aug, 2015	Chopped
H	17 Aug, 2015	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zdiA01	24 Aug, 2015	3.40.50.300	Assigned
4zdiA02	24 Aug, 2015	3.40.50.880	Assigned
4zdiB01	24 Aug, 2015	3.40.50.300	Assigned
4zdiB02	24 Aug, 2015	3.40.50.880	Assigned
4zdiC01	24 Aug, 2015	3.40.50.300	Assigned
4zdiC02	24 Aug, 2015	3.40.50.880	Assigned
4zdiD01	24 Aug, 2015	3.40.50.300	Assigned
4zdiD02	24 Aug, 2015	3.40.50.880	Assigned
4zdiE01	24 Aug, 2015	3.40.50.300	Assigned
4zdiE02	24 Aug, 2015	3.40.50.880	Assigned
4zdiF01	24 Aug, 2015	3.40.50.300	Assigned
4zdiF02	24 Aug, 2015	3.40.50.880	Assigned
4zdiG01	24 Aug, 2015	3.40.50.300	Assigned
4zdiG02	24 Aug, 2015	3.40.50.880	Assigned
4zdiH01	24 Aug, 2015	3.40.50.300	Assigned
4zdiH02	24 Aug, 2015	3.40.50.880	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase
P9WHK7	PYRG_MYCTU	Mycobacterium tuberculosis H37Rv	CTP synthase