PDB 4z16

PDB Information

PDB4Z16
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Development of Selective Covalent Janus Kinase 3 Inhibitors.
Tan, L., Akahane, K., McNally, R., Reyskens, K.M., Ficarro, S.B., Liu, S., Herter-Sprie, G.S., Koyama, S., Pattison, M.J., Labella, K., Johannessen, L., Akbay, E.A., Wong, K.K., Frank, D.A., Marto, J.A., Look, T.A., Arthur, J.S., Eck, M.J., Gray, N.S.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-03-26
Resolution2.900
CATH Insert Date10 Apr, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4z16A01 02 May, 2016 3.30.200.20 Assigned
4z16A02 02 May, 2016 1.10.510.10 Assigned
4z16B01 02 May, 2016 3.30.200.20 Assigned
4z16B02 02 May, 2016 1.10.510.10 Assigned
4z16C01 02 May, 2016 3.30.200.20 Assigned
4z16C02 02 May, 2016 1.10.510.10 Assigned
4z16D01 02 May, 2016 3.30.200.20 Assigned
4z16D02 02 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
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