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PDB Information

PDB4YOA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
The L33F darunavir resistance mutation acts as a molecular anchor reducing the flexibility of the HIV-1 protease 30s and 80s loops.
Kuiper, B.D., Keusch, B.J., Dewdney, T.G., Chordia, P., Ross, K., Brunzelle, J.S., Kovari, I.A., MacArthur, R., Salimnia, H., Kovari, L.C.
Biochem Biophys Rep
HeaderHydrolase/Hydrolase Inhibitor
Released2015-03-11
Resolution1.700
CATH Insert Date26 Jul, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 27 Jul, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4yoaA00 30 Jul, 2015 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q5RTL1 Q5RTL1_9HIV1 Human immunodeficiency virus 1 Protease
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