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PDB 4yo6

PDB Information

PDB4YO6
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHomo sapiens
Primary Citation
Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation.
McElroy, W.T., Tan, Z., Ho, G., Paliwal, S., Li, G., Seganish, W.M., Tulshian, D., Tata, J., Fischmann, T.O., Sondey, C., Bian, H., Bober, L., Jackson, J., Garlisi, C.G., Devito, K., Fossetta, J., Lundell, D., Niu, X.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-03-11
Resolution2.320
CATH Insert Date28 Jun, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4yo6A01 22 Jul, 2015 3.30.200.20 Assigned
4yo6A02 22 Jul, 2015 1.10.510.10 Assigned
4yo6B01 22 Jul, 2015 3.30.200.20 Assigned
4yo6B02 22 Jul, 2015 1.10.510.10 Assigned
4yo6C01 22 Jul, 2015 3.30.200.20 Assigned
4yo6C02 22 Jul, 2015 1.10.510.10 Assigned
4yo6D01 22 Jul, 2015 3.30.200.20 Assigned
4yo6D02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
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