×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 4ylu

PDB Information

PDB4YLU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMiddle East respiratory syndrome coronavirus
Primary Citation
Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
Tomar, S., Johnston, M.L., St John, S.E., Osswald, H.L., Nyalapatla, P.R., Paul, L.N., Ghosh, A.K., Denison, M.R., Mesecar, A.D.
J.Biol.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-03-05
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4yluA01 22 Jul, 2015 2.40.10.10 Assigned
4yluA02 22 Jul, 2015 2.40.10.10 Assigned
4yluA03 22 Jul, 2015 1.10.1840.10 Assigned
4yluB01 19 Oct, 2016 2.40.10.10 Assigned
4yluB02 19 Oct, 2016 2.40.10.10 Assigned
4yluB03 19 Oct, 2016 1.10.1840.10 Assigned
4yluC01 20 Oct, 2016 2.40.10.10 Assigned
4yluC02 20 Oct, 2016 2.40.10.10 Assigned
4yluC03 20 Oct, 2016 1.10.1840.10 Assigned
4yluD01 20 Oct, 2016 2.40.10.10 Assigned
4yluD02 20 Oct, 2016 2.40.10.10 Assigned
4yluD03 20 Oct, 2016 1.10.1840.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
V9TU12 V9TU12_9BETC Middle East respiratory syndrome-related coronavirus Orf1a
V9TU12 V9TU12_9BETC Middle East respiratory syndrome-related coronavirus Orf1a
V9TU12 V9TU12_9BETC Middle East respiratory syndrome-related coronavirus Orf1a
V9TU12 V9TU12_9BETC Middle East respiratory syndrome-related coronavirus Orf1a
CATH-Gene3D is a Global Biodata Core Resource Learn more...