PDB Information

PDB4YLK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A.
Falke, H., Chaikuad, A., Becker, A., Loaec, N., Lozach, O., Abu Jhaisha, S., Becker, W., Jones, P.G., Preu, L., Baumann, K., Knapp, S., Meijer, L., Kunick, C.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-03-05
Resolution1.400
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ylkA01 22 Jul, 2015 3.30.200.20 Assigned
4ylkA02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A