PDB 4yd0

PDB Information

PDB4YD0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceInfluenza A virus
Primary Citation
Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors.
Boyd, M.J., Bandarage, U.K., Bennett, H., Byrn, R.R., Davies, I., Gu, W., Jacobs, M., Ledeboer, M.W., Ledford, B., Leeman, J.R., Perola, E., Wang, T., Bennani, Y., Clark, M.P., Charifson, P.S.
Bioorg.Med.Chem.Lett.
HeaderTranscription/Inhibitor
Released2015-02-20
Resolution2.620
CATH Insert Date28 Jun, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4yd0A00 22 Jul, 2015 Holding pen

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q30NP1 PB2_I75A0 Influenza A virus (A/Beijing/39/1975(H3N2)) Polymerase basic protein 2
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