PDB 4yd0

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Overview

PDB Information

PDB	4YD0
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Influenza A virus
Primary Citation	Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors. Boyd, M.J., Bandarage, U.K., Bennett, H., Byrn, R.R., Davies, I., Gu, W., Jacobs, M., Ledeboer, M.W., Ledford, B., Leeman, J.R., Perola, E., Wang, T., Bennani, Y., Clark, M.P., Charifson, P.S. Bioorg.Med.Chem.Lett.
Header	Transcription/Inhibitor
Released	2015-02-20
Resolution	2.620
CATH Insert Date	28 Jun, 2015

PDB Images (3)

Image of CATH 4yd0

4yd0

PDB 4yd0

Image of CATH 4yd0A

4yd0A

PDB Chain 4yd0A

Image of CATH 4yd0A00

4yd0A00

CATH Domain 4yd0A00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4yd0A00	22 Jul, 2015		Holding pen

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q30NP1	PB2_I75A0	Influenza A virus (A/Beijing/39/1975(H3N2))	Polymerase basic protein 2