PDB 4yab

PDB Links
Overview

PDB Information

PDB	4YAB
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. Palmer, W.S., Poncet-Montange, G., Liu, G., Petrocchi, A., Reyna, N., Subramanian, G., Theroff, J., Yau, A., Kost-Alimova, M., Bardenhagen, J.P., Leo, E., Shepard, H.E., Tieu, T.N., Shi, X., Zhan, Y., Zhao, S., Barton, M.C., Draetta, G., Toniatti, C., Jones, P., Geck Do, M., Andersen, J.N. J.Med.Chem.
Header	Transcription/Transcription Inhibitor
Released	2015-02-17
Resolution	1.900
CATH Insert Date	28 Jun, 2015

PDB Images (7)

Image of CATH 4yab

4yab

PDB 4yab

Image of CATH 4yabA

4yabA

PDB Chain 4yabA

Image of CATH 4yabB

4yabB

PDB Chain 4yabB

Image of CATH 4yabA01

4yabA01

CATH Domain 4yabA01

Image of CATH 4yabA02

4yabA02

CATH Domain 4yabA02

Image of CATH 4yabB01

4yabB01

CATH Domain 4yabB01

Image of CATH 4yabB02

4yabB02

CATH Domain 4yabB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4yabA01	22 Jul, 2015	3.30.40.10	Assigned
4yabA02	22 Jul, 2015	1.20.920.10	Assigned
4yabB01	22 Jul, 2015	3.30.40.10	Assigned
4yabB02	22 Jul, 2015	1.20.920.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O15164	TIF1A_HUMAN	Homo sapiens	Transcription intermediary factor 1-alpha
O15164	TIF1A_HUMAN	Homo sapiens	Transcription intermediary factor 1-alpha