PDB 4xyc

PDB Information

PDB4XYC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceMycobacterium tuberculosis
Primary Citation
Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies.
Couturier, C., Silve, S., Morales, R., Pessegue, B., Llopart, S., Nair, A., Bauer, A., Scheiper, B., Poverlein, C., Ganzhorn, A., Lagrange, S., Bacque, E.
Bioorg.Med.Chem.Lett.
HeaderLigase/Ligase Inhibitor
Released2015-02-02
Resolution3.300
CATH Insert Date28 Jun, 2015

PDB Images (73)

PDB Prints

PDB Chains (24)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped
F 29 Jun, 2015 Chopped
G 29 Jun, 2015 Chopped
H 29 Jun, 2015 Chopped
I 29 Jun, 2015 Chopped
J 29 Jun, 2015 Chopped
K 29 Jun, 2015 Chopped
L 29 Jun, 2015 Chopped
M 29 Jun, 2015 Chopped
N 29 Jun, 2015 Chopped
O 29 Jun, 2015 Chopped
P 29 Jun, 2015 Chopped
Q 29 Jun, 2015 Chopped
R 29 Jun, 2015 Chopped
S 29 Jun, 2015 Chopped
T 29 Jun, 2015 Chopped
U 29 Jun, 2015 Chopped
V 29 Jun, 2015 Chopped
W 29 Jun, 2015 Chopped
X 29 Jun, 2015 Chopped

CATH Domains (48)

Domain ID Date inserted into CATH Superfamily CATH Status
4xycA01 22 Jul, 2015 3.10.20.70 Assigned
4xycA02 22 Jul, 2015 3.30.590.10 Assigned
4xycB01 22 Jul, 2015 3.10.20.70 Assigned
4xycB02 22 Jul, 2015 3.30.590.10 Assigned
4xycC01 22 Jul, 2015 3.10.20.70 Assigned
4xycC02 22 Jul, 2015 3.30.590.10 Assigned
4xycD01 22 Jul, 2015 3.10.20.70 Assigned
4xycD02 22 Jul, 2015 3.30.590.10 Assigned
4xycE01 22 Jul, 2015 3.10.20.70 Assigned
4xycE02 22 Jul, 2015 3.30.590.10 Assigned
4xycF01 22 Jul, 2015 3.10.20.70 Assigned
4xycF02 22 Jul, 2015 3.30.590.10 Assigned
4xycG01 22 Jul, 2015 3.10.20.70 Assigned
4xycG02 22 Jul, 2015 3.30.590.10 Assigned
4xycH01 22 Jul, 2015 3.10.20.70 Assigned
4xycH02 22 Jul, 2015 3.30.590.10 Assigned
4xycI01 22 Jul, 2015 3.10.20.70 Assigned
4xycI02 22 Jul, 2015 3.30.590.10 Assigned
4xycJ01 22 Jul, 2015 3.10.20.70 Assigned
4xycJ02 22 Jul, 2015 3.30.590.10 Assigned
4xycK01 22 Jul, 2015 3.10.20.70 Assigned
4xycK02 22 Jul, 2015 3.30.590.10 Assigned
4xycL01 22 Jul, 2015 3.10.20.70 Assigned
4xycL02 22 Jul, 2015 3.30.590.10 Assigned
4xycM01 22 Jul, 2015 3.10.20.70 Assigned
4xycM02 22 Jul, 2015 3.30.590.10 Assigned
4xycN01 22 Jul, 2015 3.10.20.70 Assigned
4xycN02 22 Jul, 2015 3.30.590.10 Assigned
4xycO01 20 Jul, 2015 3.10.20.70 Assigned
4xycO02 20 Jul, 2015 3.30.590.10 Assigned
4xycP01 22 Jul, 2015 3.10.20.70 Assigned
4xycP02 22 Jul, 2015 3.30.590.10 Assigned
4xycQ01 22 Jul, 2015 3.10.20.70 Assigned
4xycQ02 22 Jul, 2015 3.30.590.10 Assigned
4xycR01 22 Jul, 2015 3.10.20.70 Assigned
4xycR02 22 Jul, 2015 3.30.590.10 Assigned
4xycS01 22 Jul, 2015 3.10.20.70 Assigned
4xycS02 22 Jul, 2015 3.30.590.10 Assigned
4xycT01 22 Jul, 2015 3.10.20.70 Assigned
4xycT02 22 Jul, 2015 3.30.590.10 Assigned
4xycU01 22 Jul, 2015 3.10.20.70 Assigned
4xycU02 22 Jul, 2015 3.30.590.10 Assigned
4xycV01 22 Jul, 2015 3.10.20.70 Assigned
4xycV02 22 Jul, 2015 3.30.590.10 Assigned
4xycW01 22 Jul, 2015 3.10.20.70 Assigned
4xycW02 22 Jul, 2015 3.30.590.10 Assigned
4xycX01 22 Jul, 2015 3.10.20.70 Assigned
4xycX02 22 Jul, 2015 3.30.590.10 Assigned

UniProtKB Entries (24)

Accession Gene ID Taxon Description
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
P9WN38 GLN1B_MYCTO Mycobacterium tuberculosis CDC1551 Glutamine synthetase
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